For the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the prophylaxis of hereditary angioedema
C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of estradiol to resemble testosterone but less one carbon at the 19 position.
NPP is an anabolic steroid that is derived from testosterone and has been used for the treatment of various medical conditions such as osteoporosis and muscle wasting diseases. However, it has also emerged as a performance-enhancing drug due to its ability to promote muscle growth, increase strength, and enhance endurance. In this article, we will explore the benefits of Nandro Phenylpropionate in detail and examine how it can help individuals achieve their fitness goals.
Because of its exceptional advantages, NPP (Nandrolone Phenylpropionate), a form of anabolic steroid, has become popular among sportsmen and bodybuilders. It is a member of the nandrolone family of steroids and differs from Deca Durabolin (Nandrolone Decanoate) in that it has an active life that is shorter and its ester is significantly shorter.
Nandrolone is an anabolic steroid occurring naturally in the human body, albeit in small quantities. Nandrolone increases production and urinary excretion of erythropoietin. It may also have a direct action on bone marrow.
Nandrolone binds to the androgen receptor to a greater degree than testosterone, but due to its inability to act on the muscle in ways unmediated by the receptor, has less overall effect on muscle growth.
NPP steroids have been reported to increase red blood cell production, which can enhance oxygen-carrying capacity and endurance. This can be particularly beneficial for athletes engaged in intense physical activities, as it may delay the onset of fatigue and improve overall performance. However, it is important to note that the use of these steroids should be approached responsibly, with proper dosage, cycle length, and consideration of potential side effects to ensure optimal results and minimize health risks.
It is an androgen and anabolic steroid, or an agonist of the androgen receptor, the biological target of androgens like testosterone. Relative to testosterone, NPP has enhanced anabolic effects and reduced androgenic effects. In addition to its anabolic and androgenic activity, NPP has low estrogenic activity (via its metabolite estradiol) and moderate progestogenic activity. Like other AAS, NPP has antigonadotropic effects, which are due to both its androgenic and progestogenic activity.
Nandrolone is an androgen receptor agonist. The drug bound to the receptor complexes which allows it to enter the nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA.
The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
NPP steroids exert their effects through various mechanisms of action, which contribute to their notable benefits in muscle growth, strength enhancement, and performance improvement. Understanding these mechanisms can provide insight into how these steroids work within the body.
Metabolism: Nandrolone is unusual in that unlike most anabolic steroids, it is not broken down into the more reactive DHT by the enzyme 5α-reductase, but rather into a less effective product known as Dihydronandrolone.
Absorption: The absorption after oral dosing is rapid for testosterone and probably for other anabolic steroids, but there is extensive first-pass hepatic metabolism for all anabolic steroids except those that are substituted at the 17-alpha position. The rate of absorption from subcutaneous or intramuscular depots depends on the product and its formulation. Absorption is slow for the lipid-soluble esters such as the cypionate or enanthate, and for oily suspensions.
Route of elimination: Urinary excretion
Half life: The elimination half-life from plasma is very short.
All medicines may cause side effects, but many people have no, or minor, side effects. Some medical conditions may interact with Nandrolone Phenpropionate.
Tell your doctor or pharmacist if you have any medical conditions.
The most common side effects of NPP consist of virilization (masculinization) in women, including symptoms such as acne, hirsutism (increased body/facial hair growth), hoarseness of the voice, and voice deepening.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.
